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Browsing School of Health Science and Technology by Issue Date

Browsing School of Health Science and Technology by Issue Date

Now showing items 21-34 of 34

Chemosensory receptors in tsetse flies provide link between chemical and behavioural ecology

Masiga, Daniel; Obiero, George; Macharia, Rosaline; Mireji, Paul O; Christoffels, Alan (2014)

Tsetse flies survive in a variety of environments across tropical Africa, often rising to large numbers, despite their low birth rate of one offspring every seven to nine days. They use olfactory receptors to process ...
Polyphenolic composition and antioxidant activity of Kenyan Tea cultivars

Karori, SM; Wachira, FN; Ngure, RM; Mireji, PO (2014)

Polyphenolic fractions in tea are potent bioactive mo lecules. In this study, the polyphenolic composition of 25 different types of Kenyan tea cultivars was de termined using the HPLC and the Folins Ciocalteus ...
Coenzyme Q10 prevented full blown splenomegaly and decreased melarsoprol-induced reactive encephalopathy in mice infected with Trypanosoma brucei rhodesiense

Nyariki, James Nyabuga; Thuita, John Kibuthu; Nyambati, Grace Kemunto; Isaac, Alfred Orina (2014)

Objective: To establish the modulatory effects of coenzyme Q10 on experimental trypanosome infections in mice and evaluate the risk of occurrence and severity of melarsoprol-induced post treatment reactive encephalopathy ...
Evaluation of the Anticonvulsant Activity of the Leaf Methanol Extract of Crassula arborescens (Mill.) Willd. (Crassulaceae) in Mice

Amabeoku, George Jimboyeka; Mbamalu, Oluchi Nneka; Davids, Tasneem; Fakude, Samukelisiwe; Gqwaka, Anda; Mbai, Fiona N; Pieterse, Reighman; Shaik, Aneesa (2014)

Crassula arborescens (Mill.) Willd. subsp. Arborescens is widely used for the treatment of various ailments including diarrhoea, corns, epilepsy and as a purgati ve. However, no information exists in any literature ...
Blood Meal Analysis and Virus Detection in Blood-Fed Mosquitoes Collected During the 2006–2007 Rift Valley Fever Outbreak in Kenya

Lutomiah, Joel; Omond, David; Masiga, Daniel; Mutai, Collins; Mireji, Paul O; Ongus, Juliette; Linthicum, Ken J; Sang, Rosemary (2014)

Background: Rift Valley fever (RVF) is a zoonosis of domestic ruminants in Africa. Blood-fed mosquitoes collected during the 2006–2007 RVF outbreak in Kenya were analyzed to determine the virus infection status and animal ...
Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis

Marucha, KK; Masiga, DK; Meuti, ME; Mireji, PO (2014)

Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between ...
RESEARCH Open Access High-resolution melting analysis reveals low Plasmodium parasitaemia infections among microscopically negative febrile patients in western Kenya

Kipanga, Purity N; Omondi, David; Mireji, Paul O; Sawa, Patrick; Masiga, Daniel K; Villinger, Jandouwe (2014)

Background: Microscopy and rapid diagnostic tests (RDTs) are common tools for diagnosing malaria, but are deficient in detecting low Plasmodium parasitaemia. A novel molecular diagnostic tool (nPCR-HRM) that combines the ...
A Novel Highly Divergent Protein Family Identified from a Viviparous Insect by RNA-seq Analysis: A Potential Target for Tsetse Fly-Specific Abortifacients

Benoit, Joshua B.; Attardo, Geoffrey M; Michalkova, Veronika; Krause, Tyler B; Bohova, Jana; Zhang, Qirui; Baumann, Aaron A; Mireji, PO; Takáč, Peter; Denlinger, David L; Ribeiro, Jose M; Aksoy, Serap (2014)

In tsetse flies, nutrients for intrauterine larval development are synthesized by the modified accessory gland (milk gland) and provided in mother's milk during lactation. Interference with at least two milk proteins has ...
Aquaporins Are Critical for Provision of Water during Lactation and Intrauterine Progeny Hydration to Maintain Tsetse Fly Reproductive Success

Benoit, Joshua B; Hansen, Immo A; Attardo, Geoffrey M; Michalková, Veronika; Mireji, Paul O; Bargul, Joel L; Drake, Lisa L; Masiga, Daniel K; Aksoy, Serap (2014)

Tsetse flies undergo drastic fluctuations in their water content throughout their adult life history due to events such as blood feeding, dehydration and lactation, an essential feature of the viviparous reproductive biology ...
Larvicidal Activity of Selected Aloe Species Against Aedes aegypti (Diptera: Culiciade)

Chore, Judith K; Obonyo, Meshack; Wachira, Francis N; Mireji, Paul O (2014)

Management of mosquito vectors by current classes of mosquitocides is relatively ineffective and necessitates prospecting for novel insecticides with different modes of action. Larvicidal activities of 15 crude extracts ...
Odorant and Gustatory Receptors in the Tsetse Fly Glossina morsitans morsitans

Obiero, George FO; Mireji, Paul O; Nyanjom, Steven RG; Christoffels, Alan; Robertson, Hugh M; Masiga, Daniel K (2014)

Tsetse flies use olfactory and gustatory responses, through odorant and gustatory receptors (ORs and GRs), to interact with their environment. Glossina morsitans morsitans genome ORs and GRs were annotated using homologs ...
Antimutagenic effect of Kenyan Tea cultivars in a bacterial test system

Mbuthia, Karori; Wachira, Francis; Ngure, Raphael; Mireji, Paul O; Wachira, Sabina (2014)

The antimutagenic effects of the aqueous tea extracts from Kenyan black, green and purple cultivars were evaluated by the Ames te st using Salmonella typhimurium tester strains TA 1538. Results obtained ...
Can we exploit and adapt indigenous knowledge and ethno-botanicals for a healthy living in the face of emerging diseases like Ebola in Africa

Suki, K. K. Mwendwa (American Journal of Clinical and Experimental Medicine, 2015-02-14)

In this essay, we attempted to catalogue and describe African indigenous knowledge, in contributing to sustainable health development in Sub Saharan Africa. In the face of poverty and threats of diseases such as ebola.We ...
Obesity and Factors that Contribute to Obesity among Pre- Adolescents Attending Day Private Primary Schools in Nairobi, Kenya

Malla, Janet Kajuju; Waudo, Prof. Judith; Kithinji, Dr. Ciriaka T. (2015-09-01)

Obesity is a diet-related condition and it refers to an abnormally high proportion of body fat. Various studies carried out in the United States reveal that obesity stems right from childhood. Childhood obesity is the most ...

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