• Comparative in silico study of congocidine congeners as potential inhibitors of African swine fever virus 

  Amwayi, Peris; Kinyanyi, Dickson; Wamalwa, Mark; Obiero, George (Plos One, 2019-08-28)

  African swine fever virus (ASFV) infection is fatal in domesticated pigs, with a mortality rate approaching 100%. This may result in economic losses and threats to food security. Currently, there are no approved vaccines ...
• In Silico Structural and Functional Prediction of African Swine Fever Virus Protein B263R Reveals Features of a TATA Binding Protein 

  Amwayi, Peris; Kinyanyi, Dickson; Obiero, George (2018-02-22)
• Assessment of genetic diversity of pumpkins (Cucurbita spp.) from western Kenya using SSR molecular markers 

  Unknown author (Springer, 2021-03-23)

  Pumpkins (Cucurbita spp.) are among most neglected and underutilized crops cultivated for food and medicine. The major constraint to pumpkin production is lack of genetically improved seeds. The current study was aimed ...
• Oral administration of Coenzyme Q10 protects mice against oxidative stress and neuro-inflammation during experimental cerebral malaria 

  Amwayi, Peris E.; Nyariki, James N.; Ochola, Lucy A.; Jillani, Ngalla E. (Elsevier, 2019-04-11)

  In animal model of experimental cerebral malaria (ECM), the genesis of neuropathology is associated with oxidative stress and inflammatory mediators. There is limited progress in the development of new approaches to the ...
• PHENOTYPIC DIVERSITY OF PUMPKINS FROM WESTERN KENYA USING FRUIT MORPHOLOGICAL CHARACTERS 

  Amwayi, Peris W.; NYABERA, L.A.; RUNO, S.M.; NZUKI, I.W. (2019-07-23)

  Pumpkin (Cucurbita spp.) is an important indigenous crop in Africa with high nutritional, medicinal and economic value. In Kenya, pumpkins still remain underutilised and neglected; as a result may face extinction. In this ...
• Coenzyme Q10 Ameliorates potassium cyanide-induced toxicosis in a mouse model 

  Amwayi, Peris; Gitonga, Francis; Biwott, Kipchumba; Gitau, Grace Wairimu (Elsevier, 2020-12-10)

  Potassium cyanide (KCN) is one of the most lethal and feared poison; which devastates cellular respiration resulting in death due to hypoxia. Several antidotes exist, but most face major limitations of safety and efficacy. ...
• Co-administration of chloroquine and coenzyme Q10 improved treatment outcome during experimental cerebral malaria 

  Amwayi, Peris; Ouko, David B.; Ochola, Lucy A.; Wairagu, Peninah M.; Orina Isaac, Alfred (J P D, 2022-01-17)

  Development of cerebral malaria (CM) is driven by parasitemia levels, harmful inflammatory response, oxidative stress and consequent breach of the blood brain barrier. Use of adjunct therapy that utilizes an antioxidant ...
• Coenzyme Q10 nullified khat-induced hepatotoxicity, nephrotoxicity and inflammation in a mouse model 

  Amwayi, Peris; Chepukosi, Kennedy; Okanya, Patrick (Heliyon, 2020-09-08)

  Ethnopharmacological relevance: The consumption of khat (Catha Edulis, Forsk) is on the rise despite the much publicized associated deleterious health effects. How chemicals present in khat, affect various physiological ...
• A Comprehensive Genetic Analysis of Candidate Genes Regulating Response to Trypanosoma congolense Infection in Mice 

  Amwayi, Peris; Goodhead, Ian; Archibald, Alan (PLOS, 2010-11-09)

  Background: African trypanosomes are protozoan parasites that cause ‘‘sleeping sickness’’ in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) ...
• Mass spectral determination of phenylacetonitrile (PAN) levels in body tissues of adult desert locust, Schistocerca gregaria 

  Amwayi, Peris W.; Masiga, Daniel K.; Govender, Prem (Elsevier, 2012-05-17)

  Wings and legs of the gregarious desert locust, Schistocerca gregaria have been shown to be release sites of phenylacetonitrile (PAN), the major adult male-produced pheromone. However, there is limited information on the ...
• Effects of urbanization on Land Surface Temperature 

  Gachahi, L.W. (2019-09)

  Rapid urbanization is currently the most important driver of climate change mainly because intense and rapid urbanization has resulted in human-induced, mostly irreversible, land use/land cover changes. As human activities ...
• Expression of Adiponectin Receptor 1 1s indicative of Favorable Prognosis in Non Small Cell Lung Carcinum 

  Wairagu (Tohoku University Medical Press, 2013-02)
• Nuclear receptor gene alteration in human induced pluripotent stem cells with hepatic differentiation propensity 

  Wairagu, Peninah M.; Itaba, Noriko; Aramaki, Natsumi (The Japan Society of Hepatology, 2014-03-13)

  Human induced pluripotent stem (hiPS) cells are an alternative cell source of regenerative medicine for liver disease. Because variations in hepatic differentiation efficacy among hiPS cells exist, it is important to ...
• Insulin priming effect on estradiol-induced breast cancer metabolism and growth 

  Wairagu, Peninah M; Phan, Ai NH; Kim, Min-Kyu (Taylor & Francis, 2015-04-01)

  Diabetes is a risk factor for breast cancer development and is associated with poor prognosis for breast cancer patients. However, the molecular and biochemical mechanisms underlying the association between diabetes ...
• Identification of Mycobacterium species in FFPE granulomatous lymphadenitis tissue using REBA Myco-ID® 

  Wairagu, P. M.; Munkhdelger, J.; Wang, H-Y. (INT J TUBERC LUNG DIS, 2013)

  SETTING: Tuberculous lymphadenitis is the most common form of ymphadenopathy; its main histopathological finding is granulomatous inflammation. OBJECTIVE: A reverse blot hybridisation assay, REBA Myco-ID®, was applied to ...
• Combined therapeutic potential of nuclear receptors with receptor tyrosine kinase inhibitors in lung cancer 

  Wairagu, Peninah M.; Park, Kwang Hwa; Kim, Jihye (ELSEIVER, 2014-03-28)

  Cancer heterogeneity is a big hurdle in achieving complete cancer treatment, which has led to the emergence of combinational therapy. In this study, we investigated the potential use of nuclear receptor (NR) ligands for ...

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