• Molecular analysis of respiratory syncytial virus reinfections in infants from coastal Kenya 

  Ochola, Rachel; Scott, Paul D.; Ngama, Mwanajuma; Okiro, Emelda A. (PMC, 2006-01-01)

  Background—Individuals are reinfected with respiratory syncytial virus (RSV) repeatedly. The nature of reinfections in relation to RSV genetic and antigenic diversity is ill defined and has implications to persistence and ...
• Comparison of Strain-Specific Antibody Responses During Primary and Secondary Infections With Respiratory Syncytial Virus 

  Ochola, Rachel; Scott, Paul D.; Sande, Charles (J Med. Viral, 2007-12-01)

  Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in infants. RSV repeatedly reinfects individuals: this may be due in part to the variability of the attachment (G) glycoprotein and ...
• Molecular Epidemiology of Respiratory Syncytial Virus in Kilifi District, Kenya 

  Ochola, Rachel; Scott, Paul D.; Ngama, Mwanajuma; Okiro, Emelda A. (Journal of Medical Virology, 2004-06-30)

  Respiratory syncytial virus (RSV) causes significant burden of disease during infancy and childhood. This study examined the genetic relatedness of RSV positive samples from child inpatients and outpatients and a birth ...
• Demographic, socio-economic and geographic determinants ofseasonal influenza vaccine uptake in rural western Kenya, 2011 

  Ochola, Rachel; Otieno, Nancy A.; Nyawanda, Bryan O. (ELSEVIER, 2014-01-22)

  tInfluenza-associated acute lower respiratory infections cause a considerable burden of disease in ruraland urban sub-Saharan Africa communities with the greatest burden among children. Currently, vacci-nation is the best ...
• The Natural History of Respiratory Syncytial Virus in a Birth Cohort: The Influence of Age and Previous Infection on Reinfection and Disease 

  Ochola, R.; Ohuma, E. O.; Okiro, E. A.; Sande, C. J. (AJE, 2012-05-08)

  This study aimed to quantify the effect of age, time since last infection, and infection history on the rate of respiratory syncytial virus infection and the effect of age and infection history on the risk of respiratory ...
• The Level and Duration of RSV-Specific Maternal IgG in Infants in Kilifi Kenya 

  Ochola, Rachel; Sande, Charles; Fegan, Gregory; Scott, Paul D. (Plos One, 2009-12-02)
• Respiratory Syncytial Virus Epidemiology in a Birth Cohort from Kilifi District, Kenya: Infection during the First Year of Life 

  Ochola, Rachel; Nokes, D. James; Okiro, Emelda A. (JID, 2004-05-27)

  We report estimates of incidence of respiratory syncytial virus (RSV) infection during the first year of life for a birth cohort from rural, coastal Kenya. A total of 338 recruits born between 21 January 2002 and 30 May ...
• Respiratory Syncytial Virus Infection and Disease in Infants and Young Children Studied from Birth in Kilifi District, Kenya 

  Ochola, Rachel; Nokes, D James; Okiro, Emelda A; Ngama, Mwanajuma (PMC, 2008-01-01)

  Background—Within the developing country setting data are few that characterise the disease burden due to RSV and which clearly define the age group to target vaccine intervention. Methods—Children numbering 635, recruited ...
• What are the most sensitive and specific sign and symptom combinations for influenza in patients hospitalized with acute respiratory illness? Results from western Kenya, January 2007–July 2010 

  OCHOLA, R.; MURRAY, E. L.; KHAGAYI, S. (Cambridge University Press, 2012-03-15)

  Influenza causes severe illness and deaths, and global surveillance systems use different clinical case definitions to identify patients for diagnostic testing. We used data collected during January 2007–July 2010 at ...
• Evaluation of fluorescent in-situ hybridization technique for diagnosis of malaria in Ahero Sub-County hospital, Kenya 

  Ochola, R.; Kandie, Regina; Njaanake, Kariuki (BMC, 2018)

  Background: Malaria is a major cause of morbidity and mortality. Treatment of malaria in a timely manner could avert deaths. Treatment ultimately relies on the rapid and accurate diagnosis. Fluorescence in situ hybridization ...
• The Burden of Influenza and RSV among Inpatients and Outpatients in Rural Western Kenya, 2009–2012 

  Ochola, Rachel; Emukule, Gideon O.; Khagayi, Sammy; Otieno, Nancy (Plos One, 2014-08)

  Background: In Kenya, detailed data on the age-specific burden of influenza and RSV are essential to inform use of limited vaccination and treatment resources. Methods: We analyzed surveillance data from August 2009 to ...
• Does the length of specimen storage affect influenza testing results by real-time reverse transcriptionpolymerase chain reaction? An analysis of influenza surveillance specimens, 2008 to 2010 

  Ochola, R.; Caselton, D. L.; Arunga, G.; Emukule, G. (2014-09-11)

  In some influenza surveillance systems, timely transport to laboratories for reverse transcription-polymerase chain reaction (RT-PCR) testing is challenging. Guidelines suggest that samples can be stored at 4°C for up to ...
• Rapid situational assessment of people who inject drugs (PWID) in Nairobi and coastal regions of Kenya: a respondent driven sampling survey 

  Oguya, Francis; Kenya, Patrick R.; Ongecha, Francisca; Mureithi, Patrick (BMC Public Health, 2021-09)

  Background: A Cross-sectional Rapid Situational Assessment of People Who Inject Drug (PWIDs) applying Respondent Driven sampling techniques (RDS) was used to recruit subjects/participants in a study aimed at assessing HIV ...
• Randomized Control Trial Study On The Effect Of Health Education In Promoting Adherence To Treatment Among The Urban And Rural Tuberculosis Patients In Kenya 

  Oguya, Francis; Mbuti, Humphrey Kimani; Mwaniki, Elizabeth; Warutere, Peterson (Research Square, 2020-11-18)

  Background: Tuberculosis is a global health concern and the incident rate in Kenya remains high. Because of the long duration of standard treatment (six months), there is a risk of treatment default by patients. Low adherence ...
• Social Demographic Factors Associated with Adherence to Treatment Among Urban and Rural Tuberculosis Patients in Kenya. 

  Oguya, Francis; Mbuti, Humphrey; Mwaniki, Elizabeth; Warutere, Peter; Midigo, Ronnie (International Journal of Medical Science and Health Research, 2020)

  Background: Tuberculosis is a Global Public Health concern with serious Economic and Social Burden to the Patient and the Household. Because of the long duration of Standard Treatment there is a Risk of Treatment Default ...
• Demographic Factors Associated with Health-Related Quality of Life Among Urban and Rural Tuberculosis Patients in Kenya 

  Francis Oguya; Humphrey Mbuti; Elizabeth Mwaniki (Bilingual Publishing, 2019-12-31)

  Background: Tuberculosis is one of the deadliest and disabling diseases in the world today. The infection exacts its greatest toll on individuals during their most productive years. TB patients record different perceived ...
• Factors associated with default from treatment among tuberculosis patients in nairobi province, Kenya: A case control study 

  Oguya, Francis; Muture, Bernard N; Keraka, Margaret N. (BMC Public Health, 2011)

  Background: Successful treatment of tuberculosis (TB) involves taking anti-tuberculosis drugs for at least six months. Poor adherence to treatment means patients remain infectious for longer, are more likely to relapse or ...
• Innovation and Technology for societal transformation - TUK 2018 

  Nyambati, G.K.; Maranga, Rosebella O.; Ozwara, Hastings (Technical University of Kenya, 2018-02-23)
• Coenzyme Q10 and endogenous antioxidants neuro-protect mice brain against deleterious effects of melarsoprol and Trypanasoma brucei rhodesiense 

  Nyambati, G.K.; Nyariki, James N.; Mireji, Paul O. (2016)

  Melarsoprol (Mel B) is the only efficacious drug against late stage Human African Trypanosomiasis (HAT), but inadvertently is very toxic and induces Post Treatment Reactive Encephalopathy (PTRE) that is lethal in 5% of the ...
• ECONOMIC DETERMINANTS OF DOMESTIC WATER MANAGEMENT AT HOUSEHOLD LEVEL ON DIARRHEAL CASES AMONG CHILDREN UNDER FIVE YEARS OF AGE IN KANGEMI, NAIROBI COUNTY 

  Nyambati, G.K.; Onyango, Isabella Sophia; Angira, Charles (IAJHMN, 2020-06-04)

  Diarrheal diseases are one of the major causes of morbidity and mortality in developing countries particularly in children. Unsafe drinking water, along with poor sanitation and hygiene, are the main contributors to an ...

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